西安市公安局文化保卫支队
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张成孝
  • 职  称:教授(博士生导师)
  • 毕业学校:日本东京工业大学(博士) 美国Jackson State University(博士后)
  • 电  话:
  • 电子邮箱:cxzhang@snnu.edu.cn
  • 研究方向:生物电分析化学

个人简介


  长期从事生物电分析化学、电化学发光分析和生物传感器的研究,曾提出电化学溶出发光分析法、电生不稳定试剂化学发光法、能量转移电化学发光分析法、均相电化学发光免疫法、纳米适体电化学发光传感器等。目前主要进行纳米电化学和电化学发光生物传感器以及环境污染评价等方面的研究工作。
  先后主持国家自然科学基金仪器专项1项、面上项目5项、陕西省政府项目4项和省部级教学研究项目5项,参与国家“863”项目3项。发表研究论文120余篇,其中SCI源期刊发表论文50余篇,出版教材4部,主持完成陕西省仪器分析精品课程,获陕西省科技进步二等奖1项、陕西省优秀教学成果奖特等奖1项和二等奖2项、中国化学会优秀青年化学奖、陕西省优秀留学回国人员奖、宝钢教育优秀教师奖等,享受国务院政府特殊津贴。


代表性成果


       Bo Sun, Honglan Qi, Fen Ma, Qiang Gao, Chengxiao Zhang*, WuJian Miao*, Double covalent coupling method for the fabrication of highly sensitive and reusable electrogenerated chemiluminescence sensors, Anal. Chem., 2010, 82(12), 5046–5052.

       Jing Zhang, Honglan Qi, Yan Li, Jia Yang, Qiang Gao, Chengxiao Zhang*, Electrogenerated chemiluminescence DNA biosensor based on hairpin DNA probe labeled with ruthenium complex, Anal. Chem. 2008, 80, 18, 2888-2894.
       Yan Li∗, Honglan Qi, Qiang Gao, Chengxiao Zhang∗∗, Label-free and sensitive electrogenerated chemiluminescence aptasensor for the determination of lysozyme, Biosen. Bioelectron. 2011,26, 2733–2736.
       Yan Li, Honglan Qi, Qiang Gao, Jia Yang, Chengxiao Zhang∗, Nanomaterial-amplified “signal off/on” electrogenerated chemiluminescence aptasensors for the detection of thrombin, Biosen. Bioelectron., 2010, 26, 754–759.   
       Dongdong Zhang, Yage Peng, Honglan Qi, Qiang Gao, Chengxiao Zhang*, Label-free electrochemical DNA biosensor array for simultaneous detection of the HIV-1 and HIV-2 oligonucleotides incorporating different hairpin-DNA probes and redox indicator, Biosen. Bioelectron., 2010, 25, 1088–1094.
       Yage Peng, Dongdong Zhang, Yan Li, Honglan Qi, Qiang Gao, Chengxiao Zhang∗, Label-free and sensitive faradic impedance aptasensor for the determination of lysozyme based on target-induced aptamer displacement, Biosen. Bioelectron., 2009, 25, 94–99.
       XiaoXia Li, Lihua Shen, Dongdong Zhang, Qiang Gao, Fen Ma, Chengxiao Zhang*, Electrochemical impedance spectroscopy for study of aptamer-thrombin interfacial interactions, Biosens. Bioelectron. 2008, 23, 11, 1624-1630.
       Yan Li, Honglan Qi, Yage Peng, Jia Yang, Chengxiao Zhang*, Electrogenerated chemiluminescence aptamer-based method for the determination of thrombin incorporating quenching of tris (2, 2-bipyridine) ruthenium by ferrocene, Electrochem. Commun. 2008, 10, 1322-1325.
       Lihua Shen, Xiaoxia Cui, Honglan Qi, and Chengxiao Zhang*, Electrogenerated chemiluminescence of ZnS nanoparticles in alkaline aqueous solution, J. Phys. Chem. C, 2007, 111, 8172-8175
       Yan Li, Honglan Qi, Yage Peng, Jia Yang, Chengxiao Zhang*, Electrogenerated chemiluminescence aptamer-based biosensing for the determination of cocaine, Electrochem. Commun. 2007, 9, 2571-2575.