个人简介

　　利用现代光谱及分子探针技术，研究建立生物大分子高灵敏度的分析检测方法，为生命科学研究及重大疾病的早期诊断提供分子水平信息。研究领域主要包括：免疫及DNA分析中纳米粒子探针的高灵敏度检测；基因单核苷酸多态性(SNP)分析；基因表达分析；microRNA高灵敏度分析及其生物功能的研究。2005年入选教育部新世纪优秀人才支持计划；2007年获得教育部全国优秀教师称号； 2009年获得国家杰出青年科学基金的资助；2011年获得教育部“长江学者与创新团队发展计划”资助。在JACS, Angew. Chem. Int. Ed., Anal. Chem., Chem. Commun. 等杂志发表研究论文40余篇。

代表性成果

 

² Bai Jie, Zhao Yunjie, Wang Zhibin, Liu Chenghui*, Wang Yucong, Li Zhengping*. Dual-Readout Fluorescent Assay of Protein Kinase Activity by Using TiO₂-Coated Magnetic Microspheres. Analytical Chemistry, 2013, 85, 4813-4821.

² Yongqiang Cheng,* Qing Du, Liyong Wang, Hailian Jia, and Zhengping Li*，Fluorescently Cationic Conjugated Polymer as an Indicator of Ligase Chain Reaction for Sensitive and Homogeneous Detection of Single Nucleotide Polymorphism. Analytical Chemistry, 2012, 84, 3739−3744.

² Cuiping Li, Zhengping Li,* Hongxia Jia and Jingli Yan, One-step ultrasensitive detection of microRNAs with loop-mediated isothermal amplification (LAMP). Chemical Communications, 2011, 47, 2595–2597.

² Jiangyan Zhang, Zhengping Li,* Hui Wang, Yucong Wang, Hongxia Jia and Jingli Yan，Ultrasensitive quantification of mature microRNAs by real-time PCR based on ligation of a ribonucleotide-modified DNA probe. Chemical Communications, 2011, 47, 9465–9467.

² Hongxia Jia, Zhengping Li*, Chenghui Liu, Yongqiang Cheng, Ultrasensitive Detection of microRNAs with Exponentially Isothermal Amplification. Angewandte Chemie International Edition, 2010, 49, 5498-5501.

² Yongqiang Cheng, Xian Zhang, Zhengping Li*, Xiaoxia Jiao, Yucong Wang, Yali Zhang, Highly Sensitive Determination of microRNA Using Target-Primed and Branched Rolling Circle Amplification. Angewandte Chemie International Edition, 2009, 48, 3268-3272.