西安市公安局文化保卫支队
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段新瑞
  • 职  称:教授
  • 毕业学校:中国科学院化学研究所
  • 电  话:029-81530782(实验室)
  • 电子邮箱:duanxr@snnu.edu.cn
  • 研究方向:生化分析与生物传感

个人简介

  2003年7月于河北大学获理学学士学位;2006 年7月于河北大学获理学硕士学位;2010年7月于中国科学院化学研究所获理学博士学位。2010年度中国科学院院长优秀奖。曾获得2011年度中国科学院优秀博士学位论文。至今在J. Am. Chem. Soc., Nat. Protoc., Adv. Mater., Anal. Chem., Chem. Commun., 等国际刊物发表文章30余篇。

  研究领域:

       1. 干细胞分离新方法

       2. 基因编码荧光小分子探针

       3. 活细胞RNA动态追踪

  主要研究手段:

  有机合成;基因工程;磁性分离;代谢标记;静电纺丝

发表论文

1. Honghong Wang, Hui Wang, Xinrui Duan*, Yuanyuan Sun, Xiangdong Wang, Zhengping Li*, Highly sensitive and multiplexed quantification of mRNA splice variants by the direct ligation of DNA probes at the exon junction and universal PCR amplification, Chem. Sci. 2017, 8, 3635-3640.

2. Mengyue Fan, Yuanyuan Zhou, Yijing Guo, Jinsheng Song*, Xinrui Duan*, Bright red fluorescent conjugated polymer nanoparticles with dibenzopyran as electron donor for cell imaging, Anal. Methods, 2017, 9, 3255–3259.

2. Yanru Li, Lingbo Sun, Hongxia Fu, Xinrui Duan*, Facile fabrication of a 3D electrospun fibrous mat by ice-templating for a tumor spheroid culture, Polym. Chem., 2016, 7, 6805-6811.

3. Lingbo Sun, Hongxia Fu, Yanru Li, Xinrui Duan*; Zhengping Li*, Rapid recognition and isolation of live colon cancer stem cells by using metabolic labeling of azido sugar and magnetic beads, Anal. Chem. 2016, 88, 3953–3958.

4. Hongxia Fu, Yanru Li, Lingbo Sun, Pan He, Xinrui Duan*, Ratiometric fluorescence azide-alkyne cycloaddition for live mammalian cell imaging, Anal. Chem. 2015, 87,11332-11336.
5. Tianyu Wang, Hongxia Fu, Xinrui Duan* and Zhengping Li* An electrospun micro/nanofibrous mesh based nontoxic sensor for optical detection of high humidity, Analytical Methods, 2015, 7, 3676.
6. Hongxia Fu and Xinrui Duan*, Highly sensitive and colorimetric detection of hydrogen sulphide by in situ formation of Ag2S@Ag nanoparticles in polyelectrolyte multilayer film, RSC advances2015, 5, 3508.

2013 & Before:
1. Xinrui Duan, Honglin Li, Hexin Chen*, Qian Wang*, Discrimination of colon cancer stem cells using noncanonical amino acid, Chem. Comm., 2012,48, 9035-9037.
2. Xinrui Duan, Libing Liu, Xuli Feng, Shu Wang*, Assemblies of Conjugated Polyelectrolytes with Proteins for Controlled Protein Photoinactivation. Adv. Mater. 2010, 22, 1602.
3. Xinrui Duan, Wei Yue, Libing Liu, Zhengping Li, Yuliang Li, Fuchu He, Daoben Zhu, Gangqiao Zhou*, Shu Wang*, Single nucleotide polymorphism (SNP) genotyping using cationic conjugated polymers in homogeneous solution. Nat. Protoc. 2009, 4, 984-991.
4. Xinrui Duan, Zhengping Li*, Fang He, Shu Wang*, A sensitive and Homogeneous SNP Detection Using Cationic Conjugated Polymers. J. Am. Chem. Soc. 2007, 129, 4154-4155.